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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA CTBP2 GDSC1000 pan-cancer AAC 0.26 2e-10
mRNA EPB41 GDSC1000 pan-cancer AAC -0.22 2e-10
mRNA GRN GDSC1000 pan-cancer AAC 0.2 2e-10
mRNA THAP9 GDSC1000 pan-cancer AAC -0.2 2e-10
mRNA PRSS23 GDSC1000 pan-cancer AAC 0.26 3e-10
mRNA BACH2 GDSC1000 pan-cancer AAC -0.21 3e-10
mRNA APEH GDSC1000 pan-cancer AAC 0.2 3e-10
mRNA TIMP2 GDSC1000 pan-cancer AAC 0.23 3e-10
mRNA FOSL2 GDSC1000 pan-cancer AAC 0.22 3e-10
mRNA INPP1 GDSC1000 pan-cancer AAC 0.21 3e-10
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