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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA PLD1 GDSC1000 pan-cancer AAC 0.22 8e-12
mRNA ELK3 GDSC1000 pan-cancer AAC 0.22 8e-12
mRNA NFYB GDSC1000 pan-cancer AAC -0.22 9e-12
mRNA HEBP1 GDSC1000 pan-cancer AAC 0.25 9e-12
mRNA HSF2 GDSC1000 pan-cancer AAC -0.22 9e-12
mRNA MYL12A GDSC1000 pan-cancer AAC 0.22 1e-11
mRNA RAB27A GDSC1000 pan-cancer AAC 0.23 1e-11
mRNA ARPC1B GDSC1000 pan-cancer AAC 0.22 1e-11
mRNA SEPT1 GDSC1000 pan-cancer AAC -0.27 1e-11
mRNA CYFIP2 GDSC1000 pan-cancer AAC -0.26 1e-11
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