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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA KIF1A GDSC1000 pan-cancer AAC -0.25 3e-13
mRNA DOCK5 GDSC1000 pan-cancer AAC 0.23 4e-13
mRNA YPEL1 GDSC1000 pan-cancer AAC -0.24 4e-13
mRNA RIMS3 GDSC1000 pan-cancer AAC -0.25 4e-13
mRNA DHX32 GDSC1000 pan-cancer AAC 0.26 5e-13
mRNA CTSA GDSC1000 pan-cancer AAC 0.25 5e-13
mRNA S100A16 GDSC1000 pan-cancer AAC 0.3 6e-13
mRNA EML6 GDSC1000 pan-cancer AAC -0.23 6e-13
mRNA JAKMIP2 GDSC1000 pan-cancer AAC -0.25 7e-13
mRNA NOL4 GDSC1000 pan-cancer AAC -0.23 7e-13
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