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RDEA119

Synonyms

SourcesNames Used
GDSC1000RDEA119
FIMMRefametinib
PharmacoGx RDEA119

External IDs

DatabaseIdentifier
Smiles: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Inchikey: RDSACQWTXKSHJT-NSHDSACASA-N
Pubchem: 44182295

FDA Approval Status

Not Approved
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Top molecular features associated with response to RDEA119


Feature TypeStandardized
Nominal ANOVA
mRNA LYST GDSC1000 pan-cancer AAC 0.25 1e-13
mRNA NT5E GDSC1000 pan-cancer AAC 0.25 1e-13
mRNA PTPRE GDSC1000 pan-cancer AAC 0.24 1e-13
mRNA EML5 GDSC1000 pan-cancer AAC -0.29 1e-13
mRNA SERPINB6 GDSC1000 pan-cancer AAC 0.26 1e-13
mRNA TSR2 GDSC1000 pan-cancer AAC -0.22 1e-13
mRNA ADGRE5 GDSC1000 pan-cancer AAC 0.24 1e-13
mRNA MICALL2 GDSC1000 pan-cancer AAC 0.28 3e-13
mRNA MMP14 GDSC1000 pan-cancer AAC 0.28 3e-13
mRNA E2F2 GDSC1000 pan-cancer AAC -0.26 3e-13
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