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Nilotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, FIMMNilotinib
CTRPv2nilotinib
PharmacoGx Nilotinib

External IDs

DatabaseIdentifier
Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Inchikey: HHZIURLSWUIHRB-UHFFFAOYSA-N
Pubchem: 644241

Annotated Targets

ABL1, KIT, BCR

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Nilotinib


Feature TypeStandardized
Nominal ANOVA
mRNA SIGLEC12 GDSC1000 pan-cancer AAC 0.4 1e-28
mRNA SIGLEC6 GDSC1000 pan-cancer AAC 0.37 8e-27
mRNA SLC6A19 CTRPv2 pan-cancer AAC 0.37 2e-26
mRNA RHAG GDSC1000 pan-cancer AAC 0.36 1e-25
mRNA EPB42 GDSC1000 pan-cancer AAC 0.36 4e-25
mRNA GYPA GDSC1000 pan-cancer AAC 0.36 4e-25
mRNA ST8SIA6 GDSC1000 pan-cancer AAC 0.36 6e-25
mRNA HBG2 GDSC1000 pan-cancer AAC 0.36 1e-24
mRNA ANK1 CTRPv2 pan-cancer AAC 0.36 3e-24
mRNA GFI1B GDSC1000 pan-cancer AAC 0.36 3e-24
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