1. Home/
  2. Compounds/
  3. ABT-263

ABT-263

Synonyms

SourcesNames Used
GDSC1000, FIMMNavitoclax
CTRPv2navitoclax
PharmacoGx ABT-263

External IDs

DatabaseIdentifier
Smiles: CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
Inchikey: JLYAXFNOILIKPP-KXQOOQHDSA-N
Pubchem: 24978538

Annotated Targets

BCL2, BCL2L2, BAD

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to ABT-263


Feature TypeStandardized
Nominal ANOVA
mRNA RP11-729L2.2 CTRPv2 pan-cancer AAC 0.27 6e-13
mRNA WDR7 CTRPv2 pan-cancer AAC 0.28 1e-12
mRNA ZNF84 CTRPv2 pan-cancer AAC 0.25 2e-12
mRNA SMAD4 CTRPv2 pan-cancer AAC 0.26 2e-12
mRNA KIAA1147 CTRPv2 pan-cancer AAC 0.25 2e-12
mRNA AC003006.7 CTRPv2 pan-cancer AAC 0.25 3e-12
mRNA SLC35E2 CTRPv2 pan-cancer AAC 0.26 4e-12
mRNA ZNF766 CTRPv2 pan-cancer AAC 0.26 4e-12
mRNA BEND5 CTRPv2 pan-cancer AAC 0.25 4e-12
mRNA SMIM17 CTRPv2 pan-cancer AAC 0.25 5e-12
Download CSV