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Methotrexate

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMMethotrexate
CTRPv2methotrexate
PharmacoGx Methotrexate

External IDs

DatabaseIdentifier
Smiles: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
Inchikey: FBOZXECLQNJBKD-ZDUSSCGKSA-N
Pubchem: 126941

Annotated Targets

DHFR

FDA Approval Status

Approved
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Top molecular features associated with response to Methotrexate


Feature TypeStandardized
Nominal ANOVA
mRNA NAGK CTRPv2 pan-cancer AAC -0.17 1e-05
mRNA INTS2 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA GCFC2 CTRPv2 pan-cancer AAC 0.16 1e-05
mRNA TMED9 CTRPv2 pan-cancer AAC -0.17 1e-05
mRNA IDS CTRPv2 pan-cancer AAC -0.17 1e-05
mRNA DLG4 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA ELL2 CTRPv2 pan-cancer AAC -0.16 1e-05
mRNA TMEM170A CTRPv2 pan-cancer AAC 0.17 1e-05
mRNA GULP1 GDSC1000 pan-cancer AAC -0.16 1e-05
mRNA ATP5G3 CTRPv2 pan-cancer AAC 0.16 1e-05
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