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Docetaxel

Synonyms

SourcesNames Used
GDSC1000, GRAYDocetaxel
gCSI, CTRPv2docetaxel
PharmacoGx Docetaxel

External IDs

DatabaseIdentifier
Smiles: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey: ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem: 148124

Annotated Targets

BCL2, MAP2, MAP4, MAPT, NR1I2, TUBB, TUBB1

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Docetaxel


Feature TypeStandardized
Nominal ANOVA
mRNA GPX8 GDSC1000 pan-cancer AAC 0.39 3e-19
mRNA GFPT2 GDSC1000 pan-cancer AAC 0.27 1e-15
mRNA CLDN3 GDSC1000 pan-cancer AAC -0.32 2e-15
mRNA ABCB1 GDSC1000 pan-cancer AAC -0.27 3e-15
mRNA RIMKLA GDSC1000 pan-cancer AAC -0.26 1e-14
mRNA DSE GDSC1000 pan-cancer AAC 0.27 3e-14
mRNA RAB31 GDSC1000 pan-cancer AAC 0.27 5e-14
mRNA SEC11C GDSC1000 pan-cancer AAC -0.25 1e-13
mRNA AXL GDSC1000 pan-cancer AAC 0.28 1e-13
mRNA PCSK2 GDSC1000 pan-cancer AAC -0.24 2e-13
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