PharmacoDB

Sources	Names Used
GDSC1000	Vinblastine
PharmacoGx	Vinblastine

Sources

Names Used

Vinblastine

PharmacoGx

Vinblastine

Database	Identifier
Smiles:	CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Inchikey:	KDQAABAKXDWYSZ-JKDPCDLQSA-N
Pubchem:	241902

Database

Identifier

Smiles:

CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O

Inchikey:

KDQAABAKXDWYSZ-JKDPCDLQSA-N

Pubchem:

Top molecular features associated with response to Vinblastine

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	B3GNT3	GDSC1000	pan-cancer	AAC	-0.12	0.005
mRNA	RCC1	GDSC1000	pan-cancer	AAC	0.098	0.005
mRNA	PRR32	GDSC1000	pan-cancer	AAC	-0.095	0.005
mRNA	MYO1B	GDSC1000	pan-cancer	AAC	0.13	0.005
mRNA	ENDOD1	GDSC1000	pan-cancer	AAC	-0.1	0.005
mRNA	PLEKHJ1	GDSC1000	pan-cancer	AAC	-0.1	0.005
mRNA	CLMN	GDSC1000	pan-cancer	AAC	-0.1	0.005
mRNA	IKBKAP	GDSC1000	pan-cancer	AAC	0.099	0.005
mRNA	SLAMF1	GDSC1000	pan-cancer	AAC	-0.1	0.005
mRNA	ITGA2B	GDSC1000	pan-cancer	AAC	-0.094	0.005