PharmacoDB

Sources	Names Used
GDSC1000	Vinblastine
PharmacoGx	Vinblastine

Sources

Names Used

Vinblastine

PharmacoGx

Vinblastine

Database	Identifier
Smiles:	CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Inchikey:	KDQAABAKXDWYSZ-JKDPCDLQSA-N
Pubchem:	241902

Database

Identifier

Smiles:

CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O

Inchikey:

KDQAABAKXDWYSZ-JKDPCDLQSA-N

Pubchem:

Top molecular features associated with response to Vinblastine

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ENTPD2	GDSC1000	pan-cancer	AAC	-0.11	0.005
mRNA	SDHAF4	GDSC1000	pan-cancer	AAC	0.094	0.005
mRNA	STRAP	GDSC1000	pan-cancer	AAC	0.097	0.005
mRNA	HEATR1	GDSC1000	pan-cancer	AAC	0.098	0.005
mRNA	AHNAK	GDSC1000	pan-cancer	AAC	0.11	0.005
mRNA	COL6A1	GDSC1000	pan-cancer	AAC	0.12	0.005
mRNA	SMURF2	GDSC1000	pan-cancer	AAC	0.1	0.005
mRNA	TDP2	GDSC1000	pan-cancer	AAC	0.099	0.005
mRNA	CCT5	GDSC1000	pan-cancer	AAC	0.098	0.005
mRNA	CADPS	GDSC1000	pan-cancer	AAC	-0.099	0.005