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AICAR

AICAR

Synonyms

Sources	Names Used
GDSC1000	AICAR
PharmacoGx	AICAR

External IDs

Database	Identifier
Smiles:	C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
Inchikey:	RTRQQBHATOEIAF-UUOKFMHZSA-N
Pubchem:	17513

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AICAR

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TGM1	GDSC1000	pan-cancer	AAC	0.078	0.03
mRNA	TSPAN4	GDSC1000	pan-cancer	AAC	-0.088	0.03
mRNA	BRK1	GDSC1000	pan-cancer	AAC	-0.075	0.03
mRNA	RREB1	GDSC1000	pan-cancer	AAC	0.076	0.03
mRNA	IGF2	GDSC1000	pan-cancer	AAC	-0.073	0.03
mRNA	SMIM4	GDSC1000	pan-cancer	AAC	-0.071	0.03
mRNA	BRAF	GDSC1000	pan-cancer	AAC	0.073	0.03
mRNA	PROS1	GDSC1000	pan-cancer	AAC	-0.078	0.03
mRNA	UXS1	GDSC1000	pan-cancer	AAC	0.075	0.03
mRNA	NUDT5	GDSC1000	pan-cancer	AAC	0.073	0.03

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