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AICAR

AICAR

Synonyms

Sources	Names Used
GDSC1000	AICAR
PharmacoGx	AICAR

External IDs

Database	Identifier
Smiles:	C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
Inchikey:	RTRQQBHATOEIAF-UUOKFMHZSA-N
Pubchem:	17513

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AICAR

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EFCAB14	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	ATP6V0E1	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	LASP1	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	TNFRSF14	GDSC1000	pan-cancer	AAC	-0.15	0.0001
mRNA	ADCY7	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	SLC26A8	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	POLG2	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	PTGES3	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	PLPPR5	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	JARID2	GDSC1000	pan-cancer	AAC	0.14	0.0001

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