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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA RP4-777O23.3 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA PLPP6 CCLE pan-cancer AAC 0.16 0.0004
mRNA SFN GDSC1000 pan-cancer AAC 0.23 0.0004
mRNA RBBP4 CTRPv2 pan-cancer AAC -0.14 0.0004
mRNA FAM104B CCLE pan-cancer AAC -0.16 0.0004
mRNA CNGA1 gCSI pan-cancer AAC 0.22 0.0004
mRNA PROX1 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA C3 gCSI pan-cancer AAC 0.22 0.0004
mRNA CKAP5 CTRPv2 pan-cancer AAC -0.12 0.0004
mRNA HNRNPR CTRPv2 pan-cancer AAC -0.13 0.0004
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