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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA MUC22 CTRPv2 pan-cancer AAC 0.25 5e-14
mRNA SPINT1 CCLE pan-cancer AAC 0.42 6e-14
mRNA PPL GDSC1000 pan-cancer AAC 0.48 6e-14
mRNA MARVELD3 CCLE pan-cancer AAC 0.42 1e-13
mRNA MAL2 CCLE pan-cancer AAC 0.44 2e-13
mRNA GRHL2 CCLE pan-cancer AAC 0.41 2e-13
mRNA SH2D3A CCLE pan-cancer AAC 0.39 3e-13
mRNA EGFR gCSI pan-cancer AAC 0.53 4e-13
mRNA EVPL CCLE pan-cancer AAC 0.38 5e-13
mRNA KRT16 CCLE pan-cancer AAC 0.34 5e-13
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