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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF488 CCLE pan-cancer AAC 0.18 0.0004
mRNA PTCD1 gCSI pan-cancer AAC -0.2 0.0004
mRNA LIFR CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA YIF1B gCSI pan-cancer AAC 0.21 0.0004
mRNA C7orf73 gCSI pan-cancer AAC -0.21 0.0004
mRNA PTMS gCSI pan-cancer AAC -0.25 0.0004
mRNA F11R CTRPv2 pan-cancer AAC 0.14 0.0004
mRNA PWWP2B CCLE pan-cancer AAC 0.18 0.0004
mRNA HSF2 CCLE pan-cancer AAC -0.17 0.0004
mRNA STK31 gCSI pan-cancer AAC 0.22 0.0004
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