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Bortezomib

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMBortezomib
gCSI, CTRPv2bortezomib
PharmacoGx Bortezomib

External IDs

DatabaseIdentifier
Smiles: B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
Inchikey: GXJABQQUPOEUTA-RDJZCZTQSA-N
Pubchem: 387447

Annotated Targets

PSMB2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB1, PSMB10, PSMB11, PSMB3, PSMB4, PSMB5, PSMB6, PSMB7, PSMB8, PSMB9, PSMD1, PSMD2, RELA

FDA Approval Status

Approved
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Top molecular features associated with response to Bortezomib


Feature TypeStandardized
Nominal ANOVA
mRNA gCSI pan-cancer AAC -0.26 8e-07
mRNA gCSI pan-cancer AAC -0.25 1e-06
mRNA gCSI pan-cancer AAC -0.25 4e-06
mRNA gCSI pan-cancer AAC -0.24 9e-06
mRNA CTRPv2 pan-cancer AAC -0.14 2e-05
mRNA CTRPv2 pan-cancer AAC -0.13 4e-05
mRNA CTRPv2 pan-cancer AAC -0.13 6e-05
mRNA CTRPv2 pan-cancer AAC -0.13 6e-05
mRNA CTRPv2 pan-cancer AAC -0.13 7e-05
mRNA CTRPv2 pan-cancer AAC -0.13 9e-05
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