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SourcesNames Used
GDSC1000, FIMM, CTRPv2BMS-754807
PharmacoGx BMS-754807

External IDs

Smiles: CC1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
Pubchem: 24785538

Annotated Targets


Cell lines tested with BMS-754807

1249 cell lines have been tested with this compound, using data from 3 dataset(s).
CAL-51 breast GDSC1000, FIMM, CTRPv24
A549 lung CTRPv23
IGROV-1 ovary FIMM, CTRPv23
RMG-I ovary GDSC1000, FIMM, CTRPv23
K-562 haematopoietic and lymphoid tissue GDSC1000, FIMM, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
SK-OV-3 ovary GDSC1000, FIMM, CTRPv23
SIG-M5 haematopoietic and lymphoid tissue GDSC1000, FIMM, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
CAL-120 breast GDSC1000, FIMM, CTRPv23
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Top molecular features associated with response to BMS-754807

Feature TypeStandardized
Nominal ANOVA
mRNA RP4-583P15.14 CTRPv2 AAC 0.32 1e-20
mRNA LIME1 CTRPv2 AAC 0.31 7e-19
mRNA IGF1R GDSC1000 AAC 0.3 2e-17
mRNA PRDM1 CTRPv2 AAC 0.29 2e-16
mRNA TXNDC5 CTRPv2 AAC 0.27 5e-15
mRNA ZC2HC1B CTRPv2 AAC 0.26 1e-14
mRNA BLOC1S5-TXNDC5 CTRPv2 AAC 0.26 2e-14
mRNA INPP4A CTRPv2 AAC 0.27 2e-14
mRNA ITM2C CTRPv2 AAC 0.26 4e-14
mRNA RP4-583P15.15 CTRPv2 AAC 0.26 6e-14
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