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Bleomycin

Synonyms

SourcesNames Used
GDSC1000Bleomycin, Bleomycin (50 uM)
CTRPv2bleomycin A2
PharmacoGx Bleomycin

External IDs

DatabaseIdentifier
Smiles: CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-]
Inchikey: WUIABRMSWOKTOF-NUAMMRKQSA-N
Pubchem: 54608728

Annotated Targets

LIG1, LIG3

Cell lines tested with Bleomycin

1305 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv24
NCI-H1299 lung GDSC1000, CTRPv24
NCI-H1869 lung GDSC1000, CTRPv24
NCI-H460 lung GDSC1000, CTRPv24
A375 skin GDSC1000, CTRPv24
CCF-STTG1 central nervous system GDSC1000, CTRPv24
NCI-H520 lung GDSC1000, CTRPv24
DU-145 prostate GDSC1000, CTRPv24
OAW-28 ovary GDSC1000, CTRPv24
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Top molecular features associated with response to Bleomycin


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM198 GDSC1000 AAC -0.28 1e-13
mRNA SLFN11 GDSC1000 AAC 0.27 3e-12
mRNA GNAO1 GDSC1000 AAC -0.26 9e-12
mRNA CHGA GDSC1000 AAC -0.29 1e-11
mRNA NFKBIA CTRPv2 AAC 0.26 2e-11
mRNA TNFRSF10B GDSC1000 AAC 0.24 4e-11
mRNA MAT2B GDSC1000 AAC 0.25 2e-10
mRNA SCG3 GDSC1000 AAC -0.25 2e-10
mRNA SVOP GDSC1000 AAC -0.22 6e-10
mRNA NCAM1 GDSC1000 AAC -0.24 8e-10
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