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BIX02189

Synonyms

SourcesNames Used
GDSC1000BIX02189
PharmacoGx BIX02189

External IDs

DatabaseIdentifier
Smiles: CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem: 46931012

Annotated Targets

MAP2K5, MAPK7

Cell lines tested with BIX02189

978 cell lines have been tested with this compound, using data from 1 dataset(s).
YMB-1-E breast GDSC10001
NCI-H2171 lung GDSC10001
SNU-61 large intestine GDSC10001
CA46 haematopoietic and lymphoid tissue GDSC10001
EJM haematopoietic and lymphoid tissue GDSC10001
MC-CAR haematopoietic and lymphoid tissue GDSC10001
LU-134-A lung GDSC10001
RKO large intestine GDSC10001
NCI-H1755 lung GDSC10001
NB13 autonomic ganglia GDSC10001
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Top molecular features associated with response to BIX02189


Feature TypeStandardized
Nominal ANOVA
mRNA A1CF GDSC1000 AAC -0.042 0.2
mRNA A2M GDSC1000 AAC -0.039 0.3
mRNA A2ML1 GDSC1000 AAC 0.097 0.003
mRNA A3GALT2 GDSC1000 AAC 0.016 0.6
mRNA A4GALT GDSC1000 AAC 0.00054 1
mRNA A4GNT GDSC1000 AAC 0.093 0.003
mRNA AAAS GDSC1000 AAC -0.048 0.1
mRNA AACS GDSC1000 AAC -0.04 0.2
mRNA AADAC GDSC1000 AAC -0.024 0.4
mRNA AADACL2 GDSC1000 AAC 0.068 0.02
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