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BIX02189

Synonyms

SourcesNames Used
GDSC1000BIX02189
PharmacoGx BIX02189

External IDs

DatabaseIdentifier
Smiles: CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem: 46931012

Annotated Targets

MAP2K5, MAPK7

Cell lines tested with BIX02189

978 cell lines have been tested with this compound, using data from 1 dataset(s).
MMAC-SF skin GDSC10001
A375 skin GDSC10001
OC-314 ovary GDSC10001
ESO26 oesophagus GDSC10001
A427 lung GDSC10001
KMS-12-BM haematopoietic and lymphoid tissue GDSC10001
NMC-G1 central nervous system GDSC10001
TOV-21G ovary GDSC10001
CMK haematopoietic and lymphoid tissue GDSC10001
CHSA0011 bone GDSC10001
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Top molecular features associated with response to BIX02189


Feature TypeStandardized
Nominal ANOVA
mRNA LCP2 GDSC1000 AAC 0.24 2e-08
mRNA DOK2 GDSC1000 AAC 0.19 2e-08
mRNA ADGRE2 GDSC1000 AAC 0.18 3e-08
mRNA PRKCB GDSC1000 AAC 0.23 3e-08
mRNA CLEC11A GDSC1000 AAC 0.18 5e-08
mRNA RNASE3 GDSC1000 AAC 0.17 5e-08
mRNA CD300LF GDSC1000 AAC 0.18 5e-08
mRNA SP140 GDSC1000 AAC -0.2 6e-08
mRNA TIFAB GDSC1000 AAC 0.16 1e-07
mRNA LILRA1 GDSC1000 AAC 0.17 1e-07
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