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BIX02189

Synonyms

SourcesNames Used
GDSC1000BIX02189
PharmacoGx BIX02189

External IDs

DatabaseIdentifier
Smiles: CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem: 46931012

Annotated Targets

MAP2K5, MAPK7

Cell lines tested with BIX02189

978 cell lines have been tested with this compound, using data from 1 dataset(s).
HCT-15 large intestine GDSC10001
SK-N-AS autonomic ganglia GDSC10001
EW-7 bone GDSC10001
BC-3 haematopoietic and lymphoid tissue GDSC10001
SAT head and neck GDSC10001
HCE-4 oesophagus GDSC10001
BB65-RCC kidney GDSC10001
PCI-38 head and neck GDSC10001
CHSA0011 bone GDSC10001
CMK haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to BIX02189


Feature TypeStandardized
Nominal ANOVA
mRNA PRRX1 GDSC1000 AAC 7.3e-05 1
mRNA STOX2 GDSC1000 AAC -6.2e-05 1
mRNA MRPL37 GDSC1000 AAC -5.2e-05 1
mRNA THBS4 GDSC1000 AAC 5e-05 1
mRNA DNALI1 GDSC1000 AAC -5e-05 1
mRNA G3BP1 GDSC1000 AAC 4.6e-05 1
mRNA KCNJ1 GDSC1000 AAC -3.2e-05 1
mRNA CDC42EP2 GDSC1000 AAC 3.7e-05 1
mRNA MRPL48 GDSC1000 AAC 2.5e-05 1
mRNA GAB1 GDSC1000 AAC -2e-05 1
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