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SourcesNames Used
PharmacoGx BIX02189

External IDs

Smiles: CN(C)Cc1cccc(NC(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(=O)N(C)C)c1
Pubchem: 46931012

Annotated Targets


Cell lines tested with BIX02189

978 cell lines have been tested with this compound, using data from 1 dataset(s).
WM1552C skin GDSC10001
VA-ES-BJ bone GDSC10001
COLO-783 skin GDSC10001
COLO-205 large intestine GDSC10001
SU-DHL-5 haematopoietic and lymphoid tissue GDSC10001
SK-MEL-30 skin GDSC10001
MES-SA endometrium GDSC10001
SNU-81 large intestine GDSC10001
BB49-HNC upper aerodigestive tract GDSC10001
OE19 oesophagus GDSC10001
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Top molecular features associated with response to BIX02189

Feature TypeStandardized
Nominal ANOVA
mRNA PRRX1 GDSC1000 AAC 7.3e-05 1
mRNA STOX2 GDSC1000 AAC -6.2e-05 1
mRNA MRPL37 GDSC1000 AAC -5.2e-05 1
mRNA THBS4 GDSC1000 AAC 5e-05 1
mRNA DNALI1 GDSC1000 AAC -5e-05 1
mRNA G3BP1 GDSC1000 AAC 4.6e-05 1
mRNA KCNJ1 GDSC1000 AAC -3.2e-05 1
mRNA CDC42EP2 GDSC1000 AAC 3.7e-05 1
mRNA MRPL48 GDSC1000 AAC 2.5e-05 1
mRNA GAB1 GDSC1000 AAC -2e-05 1
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