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Bicalutamide

Synonyms

SourcesNames Used
GDSC1000, FIMMBicalutamide
PharmacoGx Bicalutamide

External IDs

DatabaseIdentifier
Smiles: CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
Inchikey: LKJPYSCBVHEWIU-UHFFFAOYSA-N
Pubchem: 2375

Annotated Targets

AR

Cell lines tested with Bicalutamide

1043 cell lines have been tested with this compound, using data from 2 dataset(s).
RMG-I ovary GDSC1000, FIMM3
KG-1 haematopoietic and lymphoid tissue GDSC1000, FIMM3
HDQ-P1 breast GDSC1000, FIMM3
MFM-223 breast GDSC1000, FIMM3
OVCAR-5 ovary GDSC1000, FIMM3
CAL-85-1 breast GDSC1000, FIMM3
K-562 haematopoietic and lymphoid tissue GDSC1000, FIMM3
MDA-MB-436 breast GDSC1000, FIMM3
Hs-578-T breast GDSC1000, FIMM3
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM3
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Tissues tested with Bicalutamide

35 tissues have been tested with this compound, using data from 2 dataset(s).
neuroblastomaGDSC10002
placentaGDSC10002
small intestineGDSC10002
miscGDSC10002
gastrointestinal tract (site indeterminate)GDSC10001
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Top molecular features associated with response to Bicalutamide


Feature TypeStandardized
Nominal ANOVA
mRNA TGFBR2 GDSC1000 AAC 0.18 4e-07
mRNA DKK1 GDSC1000 AAC 0.18 3e-06
mRNA FEZF2 GDSC1000 AAC 0.15 5e-06
mRNA ECM2 GDSC1000 AAC 0.15 2e-05
mRNA PLAU GDSC1000 AAC 0.17 3e-05
mRNA TRIM24 GDSC1000 AAC -0.14 4e-05
mRNA FOSL1 GDSC1000 AAC 0.15 4e-05
mRNA TNKS FIMM AAC 0.63 4e-05
mRNA UNC80 GDSC1000 AAC -0.14 5e-05
mRNA HRH1 GDSC1000 AAC 0.15 5e-05
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