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Bicalutamide

Synonyms

SourcesNames Used
GDSC1000, FIMMBicalutamide
PharmacoGx Bicalutamide

External IDs

DatabaseIdentifier
Smiles: CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
Inchikey: LKJPYSCBVHEWIU-UHFFFAOYSA-N
Pubchem: 2375

Annotated Targets

AR

Cell lines tested with Bicalutamide

1043 cell lines have been tested with this compound, using data from 2 dataset(s).
RMG-I ovary GDSC1000, FIMM3
KG-1 haematopoietic and lymphoid tissue GDSC1000, FIMM3
HDQ-P1 breast GDSC1000, FIMM3
MFM-223 breast GDSC1000, FIMM3
OVCAR-5 ovary GDSC1000, FIMM3
CAL-85-1 breast GDSC1000, FIMM3
K-562 haematopoietic and lymphoid tissue GDSC1000, FIMM3
MDA-MB-436 breast GDSC1000, FIMM3
Hs-578-T breast GDSC1000, FIMM3
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM3
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Top molecular features associated with response to Bicalutamide


Feature TypeStandardized
Nominal ANOVA
mRNA EMP1 GDSC1000 AAC 0.15 0.0001
mRNA KLHL5 GDSC1000 AAC 0.13 0.0001
mRNA EXT1 GDSC1000 AAC 0.17 0.0002
mRNA ZNF33A GDSC1000 AAC -0.14 0.0002
mRNA HSPB7 GDSC1000 AAC 0.12 0.0002
mRNA BDNF GDSC1000 AAC 0.14 0.0002
mRNA AP3S2 FIMM AAC 0.6 0.0002
mRNA CASP8 GDSC1000 AAC 0.14 0.0003
mRNA KRT6B GDSC1000 AAC 0.13 0.0003
mRNA NDUFS8 GDSC1000 AAC 0.12 0.0003
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