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Bicalutamide

Synonyms

SourcesNames Used
GDSC1000, FIMMBicalutamide
PharmacoGx Bicalutamide

External IDs

DatabaseIdentifier
Smiles: CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
Inchikey: LKJPYSCBVHEWIU-UHFFFAOYSA-N
Pubchem: 2375

Annotated Targets

AR

Cell lines tested with Bicalutamide

1043 cell lines have been tested with this compound, using data from 2 dataset(s).
RMG-I ovary GDSC1000, FIMM3
KG-1 haematopoietic and lymphoid tissue GDSC1000, FIMM3
HDQ-P1 breast GDSC1000, FIMM3
MFM-223 breast GDSC1000, FIMM3
OVCAR-5 ovary GDSC1000, FIMM3
CAL-85-1 breast GDSC1000, FIMM3
K-562 haematopoietic and lymphoid tissue GDSC1000, FIMM3
MDA-MB-436 breast GDSC1000, FIMM3
Hs-578-T breast GDSC1000, FIMM3
ML-2 haematopoietic and lymphoid tissue GDSC1000, FIMM3
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Top molecular features associated with response to Bicalutamide


Feature TypeStandardized
Nominal ANOVA
mRNA ATG7 GDSC1000 AAC 0.13 6e-05
mRNA GPX8 GDSC1000 AAC 0.19 7e-05
mRNA NNMT GDSC1000 AAC 0.16 7e-05
mRNA CXCL2 GDSC1000 AAC 0.15 7e-05
mRNA MS4A12 GDSC1000 AAC 0.13 8e-05
mRNA ITGA3 GDSC1000 AAC 0.16 8e-05
mRNA VEGFC GDSC1000 AAC 0.16 9e-05
mRNA NT5E GDSC1000 AAC 0.14 0.0001
mRNA TNFRSF1A GDSC1000 AAC 0.14 0.0001
mRNA GGCX GDSC1000 AAC 0.15 0.0001
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