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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

Cell lines tested with ZSTK474

1285 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
P3HR-1 haematopoietic and lymphoid tissue GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA NDFIP1 GDSC1000 AAC -0.19 2e-09
mRNA BMF CTRPv2 AAC 0.22 4e-09
mRNA LRMP GDSC1000 AAC 0.28 9e-09
mRNA RCSD1 GDSC1000 AAC 0.29 1e-08
mRNA NCKAP1L GDSC1000 AAC 0.28 4e-08
mRNA ARID4B GDSC1000 AAC 0.17 7e-08
mRNA STPG1 GDSC1000 AAC -0.16 1e-07
mRNA THEM4 GDSC1000 AAC -0.17 2e-07
mRNA CYB561A3 CTRPv2 AAC 0.2 2e-07
mRNA GDF11 GDSC1000 AAC 0.17 3e-07
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