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Zibotentan

Synonyms

SourcesNames Used
GDSC1000Zibotentan
PharmacoGx Zibotentan

External IDs

DatabaseIdentifier
Smiles: COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(cc1)-c1nnco1
Pubchem: 9910224

Annotated Targets

EDNRA

Cell lines tested with Zibotentan

978 cell lines have been tested with this compound, using data from 1 dataset(s).
TOV-112D ovary GDSC10001
HCC202 breast GDSC10001
NB5 autonomic ganglia GDSC10001
TE-9 oesophagus GDSC10001
NCI-H661 lung GDSC10001
DK-MG central nervous system GDSC10001
LN-405 central nervous system GDSC10001
DJM-1 skin GDSC10001
NCI-H847 lung GDSC10001
M059J central nervous system GDSC10001
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Top molecular features associated with response to Zibotentan


Feature TypeStandardized
Nominal ANOVA
mRNA ST8SIA6 GDSC1000 AAC 0.21 4e-11
mRNA CFAP161 GDSC1000 AAC 0.2 7e-10
mRNA CA1 GDSC1000 AAC 0.2 1e-09
mRNA KLF1 GDSC1000 AAC 0.19 7e-09
mRNA GATA1 GDSC1000 AAC 0.19 1e-08
mRNA ITGA2B GDSC1000 AAC 0.18 3e-08
mRNA CMTM5 GDSC1000 AAC 0.18 3e-08
mRNA GYPA GDSC1000 AAC 0.18 4e-08
mRNA FAM65C GDSC1000 AAC 0.17 2e-07
mRNA HBG2 GDSC1000 AAC 0.17 3e-07
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