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YK 4-279

Synonyms

SourcesNames Used
GDSC1000, CTRPv2YK 4-279
PharmacoGx YK 4-279

External IDs

DatabaseIdentifier
Smiles: COc1ccc(cc1)C(=O)CC1(O)C(=O)Nc2c1c(Cl)ccc2Cl

Annotated Targets

EWSR1, FLI1, DHX9, ERG, ETV1

Cell lines tested with YK 4-279

1204 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
NCI-H1869 lung GDSC1000, CTRPv23
HeLa cervix GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
IGROV-1 ovary GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
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Top molecular features associated with response to YK 4-279


Feature TypeStandardized
Nominal ANOVA
mRNA BCL2L1 CTRPv2 AAC -0.23 1e-11
mRNA CELF4 GDSC1000 AAC -0.26 3e-11
mRNA ZBTB5 CTRPv2 AAC 0.22 9e-11
mRNA GART GDSC1000 AAC 0.23 2e-10
mRNA HNRNPA1 CTRPv2 AAC 0.23 3e-10
mRNA MYOF CTRPv2 AAC -0.23 5e-10
mRNA RILPL2 GDSC1000 AAC 0.26 6e-10
mRNA RP11-426L16.10 CTRPv2 AAC -0.23 7e-10
mRNA RACK1 GDSC1000 AAC 0.22 8e-10
mRNA MANBAL CTRPv2 AAC -0.25 8e-10
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