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Y-39983

Synonyms

SourcesNames Used
GDSC1000Y-39983
PharmacoGx Y-39983

External IDs

DatabaseIdentifier
Smiles: C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
Pubchem: 9810884

Annotated Targets

ROCK1, ROCK2

Cell lines tested with Y-39983

978 cell lines have been tested with this compound, using data from 1 dataset(s).
CAL-27 upper aerodigestive tract GDSC10001
LB771-HNC upper aerodigestive tract GDSC10001
ESO26 oesophagus GDSC10001
MFH-ino soft tissue GDSC10001
QGP-1 pancreas GDSC10001
DOV13 ovary GDSC10001
SW948 large intestine GDSC10001
EN endometrium GDSC10001
NCI-H2135 lung GDSC10001
COLO-783 skin GDSC10001
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Top molecular features associated with response to Y-39983


Feature TypeStandardized
Nominal ANOVA
mRNA LMAN2 GDSC1000 AAC -0.16 2e-07
mRNA PPP1R27 GDSC1000 AAC 0.16 3e-07
mRNA NKTR GDSC1000 AAC 0.18 6e-07
mRNA CCDC66 GDSC1000 AAC 0.17 1e-06
mRNA NQO1 GDSC1000 AAC -0.2 1e-06
mRNA HNRNPH3 GDSC1000 AAC 0.16 1e-06
mRNA GTSF1L GDSC1000 AAC 0.16 2e-06
mRNA SLC4A1 GDSC1000 AAC 0.15 2e-06
mRNA PRPF4B GDSC1000 AAC 0.16 3e-06
mRNA METTL14 GDSC1000 AAC 0.16 4e-06
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