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XMD8-92

Synonyms

SourcesNames Used
GDSC1000XMD8-92
PharmacoGx XMD8-92

External IDs

DatabaseIdentifier
Smiles: CCOc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCC(O)CC1
Pubchem: 46843772

Annotated Targets

DCLK2, MAPK7, PLK4, TNK1

Cell lines tested with XMD8-92

522 cell lines have been tested with this compound, using data from 1 dataset(s).
K2 thyroid GDSC10001
CAL-12T lung GDSC10001
NCI-H1568 lung GDSC10001
LC-1-sq lung GDSC10001
SNG-M endometrium GDSC10001
WM1552C skin GDSC10001
IOSE-397 ovary GDSC10001
RVH-421 skin GDSC10001
H2869 pleura GDSC10001
SCC-15 upper aerodigestive tract GDSC10001
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Top molecular features associated with response to XMD8-92


Feature TypeStandardized
Nominal ANOVA
mRNA PACS1 GDSC1000 AAC 0.21 8e-06
mRNA TFAP2E GDSC1000 AAC 0.18 9e-05
mRNA CHSY1 GDSC1000 AAC 0.18 0.0003
mRNA DBH GDSC1000 AAC -0.21 0.0004
mRNA SSX3 GDSC1000 AAC 0.16 0.0004
mRNA CHRNA3 GDSC1000 AAC -0.27 0.0005
mRNA PCBD1 GDSC1000 AAC -0.2 0.0005
mRNA PPP2R2C GDSC1000 AAC -0.18 0.0006
mRNA DPP6 GDSC1000 AAC -0.17 0.0006
mRNA KCTD6 GDSC1000 AAC -0.17 0.0007
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