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SourcesNames Used
PharmacoGx XMD8-85

External IDs

Smiles: COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

Cell lines tested with XMD8-85

423 cell lines have been tested with this compound, using data from 1 dataset(s).
NB(TU)1-10 neuroblastoma GDSC10001
RPMI-6666 haematopoietic and lymphoid tissue GDSC10001
CGTH-W-1 thyroid GDSC10001
EW-1 bone GDSC10001
MMAC-SF skin GDSC10001
KALS-1 central nervous system GDSC10001
D-502MG central nervous system GDSC10001
LB2518-MEL skin GDSC10001
KY821 haematopoietic and lymphoid tissue GDSC10001
NB6 autonomic ganglia GDSC10001
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Top molecular features associated with response to XMD8-85

Feature TypeStandardized
Nominal ANOVA
mRNA C5orf46 GDSC1000 AAC 0.31 4e-08
mRNA COL1A1 GDSC1000 AAC 0.3 9e-07
mRNA MORF4L2 GDSC1000 AAC -0.28 2e-06
mRNA PDGFRB GDSC1000 AAC 0.25 9e-06
mRNA NID2 GDSC1000 AAC 0.24 9e-06
mRNA BGN GDSC1000 AAC 0.24 1e-05
mRNA FRMD7 GDSC1000 AAC 0.21 5e-05
mRNA COL5A1 GDSC1000 AAC 0.27 6e-05
mRNA VIPR2 GDSC1000 AAC 0.2 6e-05
mRNA ACTC1 GDSC1000 AAC 0.2 8e-05
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