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XL-184

Synonyms

SourcesNames Used
GDSC1000XL-184
PharmacoGx XL-184

External IDs

DatabaseIdentifier
Pubchem: 25102847

Annotated Targets

MET, KDR, KIT, TEK

Cell lines tested with XL-184

978 cell lines have been tested with this compound, using data from 1 dataset(s).
MDA-MB-415 breast GDSC10001
Mewo skin GDSC10001
SW962 vulva GDSC10001
EW-7 bone GDSC10001
H-EMC-SS bone GDSC10001
WSU-DLCL2 haematopoietic and lymphoid tissue GDSC10001
ML-2 haematopoietic and lymphoid tissue GDSC10001
OMC-1 cervix GDSC10001
NCI-H810 lung GDSC10001
RC-K8 haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to XL-184


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS57 GDSC1000 AAC 0.38 2e-26
mRNA FLT3 GDSC1000 AAC 0.35 2e-24
mRNA TIFAB GDSC1000 AAC 0.32 1e-22
mRNA PPP1R27 GDSC1000 AAC 0.31 1e-21
mRNA OCSTAMP GDSC1000 AAC 0.31 1e-20
mRNA MS4A6A GDSC1000 AAC 0.31 6e-20
mRNA CD300LF GDSC1000 AAC 0.28 7e-16
mRNA CCR2 GDSC1000 AAC 0.27 6e-15
mRNA CCL23 GDSC1000 AAC 0.26 2e-14
mRNA CSF1R GDSC1000 AAC 0.26 2e-14
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