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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

Cell lines tested with XAV-939

959 cell lines have been tested with this compound, using data from 1 dataset(s).
NUGC-4 stomach GDSC10001
NCI-H1581 lung GDSC10001
LC-1-sq lung GDSC10001
TGW autonomic ganglia GDSC10001
EMC-BAC-1 oesophagus GDSC10001
SU-DHL-10 haematopoietic and lymphoid tissue GDSC10001
EW-24 bone GDSC10001
SW962 vulva GDSC10001
MN-60 haematopoietic and lymphoid tissue GDSC10001
PL4 pancreas GDSC10001
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA FGD6 GDSC1000 AAC 0.21 5e-08
mRNA TBL1XR1 GDSC1000 AAC -0.15 6e-06
mRNA C7orf72 GDSC1000 AAC 0.15 1e-05
mRNA PHLDB2 GDSC1000 AAC 0.18 1e-05
mRNA ZNF621 GDSC1000 AAC -0.14 3e-05
mRNA RAB40B GDSC1000 AAC -0.15 4e-05
mRNA TMEM52 GDSC1000 AAC -0.15 4e-05
mRNA PALLD GDSC1000 AAC 0.18 5e-05
mRNA CBX7 GDSC1000 AAC -0.14 6e-05
mRNA SLC25A38 GDSC1000 AAC -0.15 9e-05
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