1. Home/
  2. Compounds/
  3. VX-680

VX-680

Synonyms

SourcesNames Used
GDSC1000, GRAY, CTRPv2VX-680
PharmacoGx VX-680

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5
Inchikey: GCIKSSRWRFVXBI-UHFFFAOYSA-N
Pubchem: 5494449

Annotated Targets

AURKA, AURKB, AURKC

Cell lines tested with VX-680

575 cell lines have been tested with this compound, using data from 3 dataset(s).
BT-474 breast GDSC1000, GRAY, CTRPv25
MDA-MB-361 breast GRAY, CTRPv24
MDA-MB-134-VI breast GDSC1000, GRAY4
MDA-MB-415 breast GRAY, CTRPv23
UACC-812 breast GRAY3
MX-1 breast GRAY3
MDA-MB-175-VII breast GRAY3
CAMA-1 breast GRAY3
HCC1187 breast GDSC1000, GRAY3
MDA-MB-453 breast GRAY, CTRPv22
Download CSV
Download Data as CSV

Top molecular features associated with response to VX-680


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPDL CTRPv2 AAC 0.58 2e-07
mRNA FAM175A CTRPv2 AAC 0.57 3e-07
mRNA RBMX CTRPv2 AAC 0.54 5e-07
mRNA ZFP69B CTRPv2 AAC 0.49 7e-07
mRNA SFPQ CTRPv2 AAC 0.5 2e-06
mRNA CBX5 CTRPv2 AAC 0.51 2e-06
mRNA DCHS2 CTRPv2 AAC 0.46 2e-06
mRNA ANKRD63 CTRPv2 AAC 0.48 2e-06
mRNA UPF2 CTRPv2 AAC 0.46 4e-06
mRNA FUBP1 CTRPv2 AAC 0.45 6e-06
Download CSV