1. Home/
  2. Compounds/
  3. VX-680

VX-680

Synonyms

SourcesNames Used
GDSC1000, GRAY, CTRPv2VX-680
PharmacoGx VX-680

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5
Inchikey: GCIKSSRWRFVXBI-UHFFFAOYSA-N
Pubchem: 5494449

Annotated Targets

AURKA, AURKB, AURKC

Cell lines tested with VX-680

575 cell lines have been tested with this compound, using data from 3 dataset(s).
LY2 breast GRAY2
Hs-578-T breast GRAY2
HCC70 breast GRAY2
HCC2185 breast GRAY2
HCC1569 breast GRAY2
HCC1428 breast GRAY2
BT-483 breast GRAY2
AU565 breast GRAY, CTRPv22
SUM225CWN breast GRAY2
SUM 159PT breast GRAY2
Download CSV
Download Data as CSV

Top molecular features associated with response to VX-680


Feature TypeStandardized
Nominal ANOVA
mRNA A1BG CTRPv2 AAC 0.0089 0.9
mRNA A1CF GDSC1000 AAC -0.046 0.4
mRNA A1CF CTRPv2 AAC 0.078 0.4
mRNA A2M CTRPv2 AAC -0.15 0.2
mRNA A2M GDSC1000 AAC -0.079 0.2
mRNA A2ML1 CTRPv2 AAC -0.27 0.1
mRNA A2ML1 GDSC1000 AAC 0.034 0.5
mRNA A3GALT2 CTRPv2 AAC 0.15 0.2
mRNA A3GALT2 GDSC1000 AAC 0.022 0.7
mRNA A4GALT CTRPv2 AAC -0.32 0.03
Download CSV