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vincristine

Synonyms

SourcesNames Used
CTRPv2vincristine
PharmacoGx vincristine

External IDs

DatabaseIdentifier
Smiles: CCC1(O)CC2CN(C1)CCc3c([nH]c4ccccc34)C(C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)C7C86CCN9CC=CC(CC)(C98)C(C(=O)OC)C7(O)C(=O)OC
Pubchem: 5978

Annotated Targets

TUBA4A, TUBB

Cell lines tested with vincristine

845 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to vincristine


Feature TypeStandardized
Nominal ANOVA
mRNA MEX3A CTRPv2 AAC 0.29 2e-15
mRNA CD63 CTRPv2 AAC -0.29 4e-15
mRNA KLHL23 CTRPv2 AAC 0.26 5e-15
mRNA RP11-426L16.10 CTRPv2 AAC -0.28 7e-15
mRNA FAM117B CTRPv2 AAC 0.25 1e-14
mRNA BCL2L1 CTRPv2 AAC -0.25 1e-14
mRNA ELAVL1 CTRPv2 AAC 0.25 2e-14
mRNA CNOT9 CTRPv2 AAC 0.24 3e-14
mRNA IRAK1BP1 CTRPv2 AAC 0.24 3e-14
mRNA MYOF CTRPv2 AAC -0.27 3e-14
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