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Vinblastine

Synonyms

SourcesNames Used
GDSC1000Vinblastine
PharmacoGx Vinblastine

External IDs

DatabaseIdentifier
Smiles: CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Inchikey: KDQAABAKXDWYSZ-JKDPCDLQSA-N
Pubchem: 241902

Annotated Targets

JUN, TUBA1A, TUBB, TUBD1, TUBE1, TUBG1

Cell lines tested with Vinblastine

895 cell lines have been tested with this compound, using data from 1 dataset(s).
Calu-3 lung GDSC10001
Sci-1 haematopoietic and lymphoid tissue GDSC10001
COR-L95 lung GDSC10001
Geo large intestine GDSC10001
IST-SL1 lung GDSC10001
P30-OHK haematopoietic and lymphoid tissue GDSC10001
EN endometrium GDSC10001
OCUB-M breast GDSC10001
MDA-MB-453 breast GDSC10001
KYSE-70 oesophagus GDSC10001
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Top molecular features associated with response to Vinblastine


Feature TypeStandardized
Nominal ANOVA
mRNA ABCB1 GDSC1000 AAC -0.33 2e-18
mRNA CLDN3 GDSC1000 AAC -0.31 2e-12
mRNA ITPRIP GDSC1000 AAC 0.22 6e-10
mRNA MTO1 GDSC1000 AAC 0.24 1e-09
mRNA ASUN GDSC1000 AAC 0.2 3e-09
mRNA SHROOM3 GDSC1000 AAC -0.24 3e-09
mRNA CMTM3 GDSC1000 AAC 0.21 2e-08
mRNA NOB1 GDSC1000 AAC 0.2 3e-08
mRNA PRR15L GDSC1000 AAC -0.23 4e-08
mRNA SC5D GDSC1000 AAC -0.19 6e-08
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