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Bexarotene

Synonyms

SourcesNames Used
GDSC1000, FIMMBexarotene
CTRPv2bexarotene
PharmacoGx Bexarotene

External IDs

DatabaseIdentifier
Smiles: CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
Inchikey: NAVMQTYZDKMPEU-UHFFFAOYSA-N
Pubchem: 82146

Annotated Targets

RXRA, RXRB, RXRG

Cell lines tested with Bexarotene

1246 cell lines have been tested with this compound, using data from 3 dataset(s).
CAL-51 breast GDSC1000, FIMM, CTRPv24
A549 lung CTRPv23
IGROV-1 ovary FIMM, CTRPv23
BT-474 breast GDSC1000, FIMM, CTRPv23
OCI-AML5 haematopoietic and lymphoid tissue GDSC1000, FIMM, CTRPv23
A375 skin GDSC1000, CTRPv23
MONO-MAC-6 haematopoietic and lymphoid tissue GDSC1000, FIMM, CTRPv23
SIG-M5 haematopoietic and lymphoid tissue GDSC1000, FIMM, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
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Top molecular features associated with response to Bexarotene


Feature TypeStandardized
Nominal ANOVA
mRNA CECR6 CTRPv2 AAC 0.27 1e-14
mRNA HAND1 CTRPv2 AAC 0.26 1e-13
mRNA UTS2B CTRPv2 AAC 0.25 4e-13
mRNA PLPPR3 CTRPv2 AAC 0.26 4e-13
mRNA GPR88 CTRPv2 AAC 0.25 5e-13
mRNA TIGIT CTRPv2 AAC 0.25 6e-13
mRNA OR52A5 CTRPv2 AAC 0.24 2e-12
mRNA PPIAL4C CTRPv2 AAC 0.24 2e-12
mRNA DOK2 CTRPv2 AAC 0.27 2e-12
mRNA TIFAB GDSC1000 AAC 0.24 3e-12
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