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TW 37

Synonyms

SourcesNames Used
GDSC1000TW 37
CTRPv2TW-37
PharmacoGx TW 37

External IDs

DatabaseIdentifier
Smiles: CC(C)C1=CC=CC=C1CC2=C(C(=C(C(=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)C4=CC=CC=C4C(C)(C)C)O)O)O
Inchikey: PQAPVTKIEGUPRN-UHFFFAOYSA-N
Pubchem: 11455910

Annotated Targets

BCL2, BCL2L1, MCL1

Cell lines tested with TW 37

1265 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
NCI-H460 lung GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
HeLa cervix GDSC1000, CTRPv23
IGROV-1 ovary GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
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Top molecular features associated with response to TW 37


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM45B GDSC1000 AAC -0.27 9e-12
mRNA OVOL2 GDSC1000 AAC -0.28 2e-11
mRNA CLDN4 GDSC1000 AAC -0.29 1e-10
mRNA METAP2 GDSC1000 AAC 0.22 1e-10
mRNA ARSK GDSC1000 AAC 0.22 3e-10
mRNA CCT4 GDSC1000 AAC 0.21 4e-10
mRNA KRTCAP3 GDSC1000 AAC -0.25 4e-10
mRNA NOC3L GDSC1000 AAC 0.2 7e-10
mRNA CLDN3 GDSC1000 AAC -0.26 7e-10
mRNA EIF3A GDSC1000 AAC 0.21 8e-10
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