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tubastatin A

Synonyms

SourcesNames Used
GDSC1000Tubastatin A
CTRPv2tubastatin A
PharmacoGx tubastatin A

External IDs

DatabaseIdentifier
Smiles: CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO
Pubchem: 49850262

Annotated Targets

HDAC6

Cell lines tested with tubastatin A

1114 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
A375 skin GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
SUIT-2 pancreas GDSC1000, CTRPv23
P3HR-1 haematopoietic and lymphoid tissue GDSC1000, CTRPv23
IGROV-1 ovary CTRPv22
Calu-3 lung GDSC1000, CTRPv22
PL-21 haematopoietic and lymphoid tissue GDSC1000, CTRPv22
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Top molecular features associated with response to tubastatin A


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGDIG CTRPv2 AAC 0.4 1e-15
mRNA IGLL1 GDSC1000 AAC 0.24 3e-12
mRNA TEX33 CTRPv2 AAC 0.31 3e-11
mRNA MALRD1 CTRPv2 AAC 0.31 5e-11
mRNA RCSD1 GDSC1000 AAC 0.33 6e-11
mRNA VPREB1 GDSC1000 AAC 0.21 6e-11
mRNA UGT2B15 CTRPv2 AAC 0.42 1e-10
mRNA RGS11 CTRPv2 AAC 0.32 1e-10
mRNA RASGRP2 GDSC1000 AAC 0.27 1e-10
mRNA RAX2 CTRPv2 AAC 0.3 1e-10
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