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triptolide

Synonyms

SourcesNames Used
CTRPv2triptolide
PharmacoGx triptolide

External IDs

DatabaseIdentifier
Smiles: CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C
Inchikey: DFBIRQPKNDILPW-CIVMWXNOSA-N
Pubchem: 107985

Annotated Targets

RELA

Cell lines tested with triptolide

842 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to triptolide


Feature TypeStandardized
Nominal ANOVA
mRNA TEX13B CTRPv2 AAC 0.19 1e-08
mRNA MAGEB16 CTRPv2 AAC 0.18 6e-08
mRNA FAM9A CTRPv2 AAC 0.18 6e-08
mRNA CCND2 CTRPv2 AAC 0.19 8e-08
mRNA GPRIN3 CTRPv2 AAC 0.18 1e-07
mRNA MYC CTRPv2 AAC 0.19 4e-07
mRNA CCDC172 CTRPv2 AAC 0.17 6e-07
mRNA TRAPPC1 CTRPv2 AAC -0.18 8e-07
mRNA MEI4 CTRPv2 AAC 0.17 1e-06
mRNA MLST8 CTRPv2 AAC 0.17 1e-06
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