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triazolothiadiazine

Synonyms

SourcesNames Used
CTRPv2triazolothiadiazine
PharmacoGx triazolothiadiazine

Annotated Targets

PDE4A, PDE4B, PDE4D

Cell lines tested with triazolothiadiazine

853 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Tissues tested with triazolothiadiazine

25 tissues have been tested with this compound, using data from 1 dataset(s).
haematopoietic and lymphoid tissueCTRPv2157
lungCTRPv2148
large intestineCTRPv249
N/ACTRPv248
central nervous systemCTRPv246
skinCTRPv245
pancreasCTRPv241
ovaryCTRPv241
breastCTRPv241
stomachCTRPv233
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Top molecular features associated with response to triazolothiadiazine


Feature TypeStandardized
Nominal ANOVA
mRNA TAF5 CTRPv2 AAC 0.26 6e-15
mRNA SMARCC1 CTRPv2 AAC 0.25 2e-14
mRNA BCL2L1 CTRPv2 AAC -0.24 4e-14
mRNA CNOT9 CTRPv2 AAC 0.24 5e-14
mRNA RBM10 CTRPv2 AAC 0.23 3e-13
mRNA RHBDF1 CTRPv2 AAC -0.26 3e-13
mRNA GMEB1 CTRPv2 AAC 0.24 4e-13
mRNA ORC1 CTRPv2 AAC 0.24 5e-13
mRNA KHDRBS1 CTRPv2 AAC 0.22 5e-13
mRNA KLHL23 CTRPv2 AAC 0.23 6e-13
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