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SourcesNames Used
PharmacoGx TPCA-1

External IDs

Smiles: NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem: 9903786

Annotated Targets


Cell lines tested with TPCA-1

1282 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
HeLa cervix GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
P3HR-1 haematopoietic and lymphoid tissue GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
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Top molecular features associated with response to TPCA-1

Feature TypeStandardized
Nominal ANOVA
mRNA NCKAP1L GDSC1000 AAC 0.35 8e-14
mRNA PRKCB GDSC1000 AAC 0.25 4e-11
mRNA ZNF100 GDSC1000 AAC 0.2 3e-10
mRNA NQO1 GDSC1000 AAC -0.23 4e-10
mRNA CCAR1 GDSC1000 AAC 0.18 2e-08
mRNA HNRNPA1L2 GDSC1000 AAC 0.17 2e-08
mRNA CA1 GDSC1000 AAC 0.15 3e-08
mRNA RBMX GDSC1000 AAC 0.18 3e-08
mRNA HS3ST4 GDSC1000 AAC 0.19 5e-08
mRNA LCP2 GDSC1000 AAC 0.21 7e-08
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