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tosedostat

Synonyms

SourcesNames Used
CTRPv2tosedostat
PharmacoGx tosedostat

External IDs

DatabaseIdentifier
Smiles: CC(C)CC(C(C(=O)NO)O)C(=O)NC(C1=CC=CC=C1)C(=O)OC2CCCC2
Inchikey: FWFGIHPGRQZWIW-SQNIBIBYSA-N
Pubchem: 15547703

Annotated Targets

ANPEP, LAP3, NPEPPS

Cell lines tested with tosedostat

795 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to tosedostat


Feature TypeStandardized
Nominal ANOVA
mRNA ZSWIM2 CTRPv2 AAC 0.24 1e-11
mRNA DAOA CTRPv2 AAC 0.23 1e-10
mRNA ABRA CTRPv2 AAC 0.22 3e-10
mRNA RP11-58C22.1 CTRPv2 AAC 0.22 3e-10
mRNA ADAMTS20 CTRPv2 AAC 0.22 1e-09
mRNA AXIN2 CTRPv2 AAC 0.23 4e-08
mRNA CTD-2535L24.2 CTRPv2 AAC 0.22 8e-08
mRNA ZIC1 CTRPv2 AAC 0.19 8e-08
mRNA NDST4 CTRPv2 AAC 0.19 2e-07
mRNA CNTNAP4 CTRPv2 AAC 0.18 4e-07
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