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TKI258

Synonyms

SourcesNames Used
CCLETKI258
PharmacoGx TKI258

External IDs

DatabaseIdentifier
Smiles: CN1CCN(CC1)C2=CC3=C(C=C2)NC(=C4C(=C5C(=NC4=O)C=CC=C5F)N)N3
Inchikey: KCOYQXZDFIIGCY-ZZEZOPTASA-N
Pubchem: 9886808

Cell lines tested with TKI258

504 cell lines have been tested with this compound, using data from 1 dataset(s).
ZR-75-30 breast CCLE1
ZR-75-1 breast CCLE1
YKG-1 central nervous system CCLE1
WM-983B skin CCLE1
WM-88 skin CCLE1
WM-793 skin CCLE1
WM-266-4 skin CCLE1
WM1799 skin CCLE1
WM-115 skin CCLE1
VMRC-RCZ kidney CCLE1
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Top molecular features associated with response to TKI258


Feature TypeStandardized
Nominal ANOVA
mRNA TYROBP CCLE AAC 0.32 1e-11
mRNA DPEP2 CCLE AAC 0.32 2e-10
mRNA C1orf228 CCLE AAC 0.31 7e-10
mRNA MS4A6A CCLE AAC 0.28 2e-09
mRNA LST1 CCLE AAC 0.32 2e-09
mRNA SLC22A16 CCLE AAC 0.29 2e-09
mRNA PRTN3 CCLE AAC 0.27 2e-09
mRNA RNASE2 CCLE AAC 0.27 4e-09
mRNA FLT3 CCLE AAC 0.27 6e-09
mRNA CSF3R CCLE AAC 0.26 1e-08
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