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tivantinib

Synonyms

SourcesNames Used
CTRPv2tivantinib
PharmacoGx tivantinib

External IDs

DatabaseIdentifier
Smiles: O=C1NC(=O)[C@H]([C@@H]1c1c[nH]c2ccccc12)c1cn2CCCc3cccc1c23
Pubchem: 11494412

Annotated Targets

MET

Cell lines tested with tivantinib

440 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
YAMATO N/A CTRPv21
TTC709 N/A CTRPv21
TM87-16 N/A CTRPv21
SYO1 N/A CTRPv21
SW982 soft tissue CTRPv21
BT16 N/A CTRPv21
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Top molecular features associated with response to tivantinib


Feature TypeStandardized
Nominal ANOVA
mRNA HNRNPM CTRPv2 AAC 0.29 1e-09
mRNA SFPQ CTRPv2 AAC 0.29 2e-09
mRNA RBM10 CTRPv2 AAC 0.28 4e-09
mRNA BEND3 CTRPv2 AAC 0.28 4e-09
mRNA CHD4 CTRPv2 AAC 0.28 6e-09
mRNA CD63 CTRPv2 AAC -0.32 1e-08
mRNA MYOF CTRPv2 AAC -0.29 1e-08
mRNA HNRNPA1 CTRPv2 AAC 0.29 1e-08
mRNA WDR33 CTRPv2 AAC 0.27 2e-08
mRNA HNRNPU CTRPv2 AAC 0.27 2e-08
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