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thalidomide

Synonyms

SourcesNames Used
CTRPv2thalidomide
PharmacoGx thalidomide

External IDs

DatabaseIdentifier
Smiles: O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13
Inchikey: UEJJHQNACJXSKW-UHFFFAOYSA-N
Pubchem: 5426

Annotated Targets

CRBN, FGFR2, NFKB1, ORM1, ORM2, PTGS2, TNF

Cell lines tested with thalidomide

431 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
YAMATO N/A CTRPv21
TTC709 N/A CTRPv21
TM87-16 N/A CTRPv21
SYO1 N/A CTRPv21
SW982 soft tissue CTRPv21
BT16 N/A CTRPv21
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Top molecular features associated with response to thalidomide


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGAP40 CTRPv2 AAC 0.26 8e-07
mRNA MRGPRD CTRPv2 AAC 0.25 1e-06
mRNA ZNF257 CTRPv2 AAC 0.23 1e-05
mRNA NPIPA5 CTRPv2 AAC 0.24 1e-05
mRNA ZNF681 CTRPv2 AAC 0.24 1e-05
mRNA NODAL CTRPv2 AAC 0.23 1e-05
mRNA CLRN2 CTRPv2 AAC 0.22 2e-05
mRNA ZNF738 CTRPv2 AAC 0.24 2e-05
mRNA CRYGN CTRPv2 AAC 0.22 2e-05
mRNA CARD18 CTRPv2 AAC 0.22 2e-05
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