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TG-101348

Synonyms

SourcesNames Used
GDSC1000TG101348
CTRPv2TG-101348
PharmacoGx TG-101348

External IDs

DatabaseIdentifier
Smiles: CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
Inchikey: JOOXLOJCABQBSG-UHFFFAOYSA-N
Pubchem: 16722836

Annotated Targets

BRD4, JAK1, JAK2, JAK3, TYK2

Cell lines tested with TG-101348

1277 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
HeLa cervix GDSC1000, CTRPv23
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Top molecular features associated with response to TG-101348


Feature TypeStandardized
Nominal ANOVA
mRNA FLT3 GDSC1000 AAC 0.21 5e-13
mRNA MYB GDSC1000 AAC 0.28 5e-12
mRNA PRSS57 GDSC1000 AAC 0.2 1e-11
mRNA BAHCC1 GDSC1000 AAC 0.17 1e-09
mRNA MLC1 GDSC1000 AAC 0.19 1e-09
mRNA BCL2A1 GDSC1000 AAC -0.19 2e-09
mRNA LAIR1 GDSC1000 AAC 0.22 3e-09
mRNA NCKAP1L GDSC1000 AAC 0.26 3e-08
mRNA MDFI GDSC1000 AAC 0.17 4e-08
mRNA C16orf54 GDSC1000 AAC 0.19 4e-08
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