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TG-100-115

Synonyms

SourcesNames Used
CTRPv2TG-100-115
PharmacoGx TG-100-115

External IDs

DatabaseIdentifier
Smiles: Nc1nc(N)c2nc(-c3cccc(O)c3)c(nc2n1)-c1cccc(O)c1
Pubchem: 10427712

Annotated Targets

PIK3CD, PIK3CG, PIK3CA, PIK3CB

Cell lines tested with TG-100-115

836 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to TG-100-115


Feature TypeStandardized
Nominal ANOVA
mRNA AC141272.1 CTRPv2 AAC 0.25 1e-12
mRNA NLRP7 CTRPv2 AAC 0.24 3e-11
mRNA STRA8 CTRPv2 AAC 0.23 1e-10
mRNA ALDH5A1 CTRPv2 AAC 0.23 2e-09
mRNA GTF2I CTRPv2 AAC 0.22 2e-09
mRNA PLEKHG2 CTRPv2 AAC 0.22 3e-09
mRNA FBXW12 CTRPv2 AAC 0.22 4e-09
mRNA ABCD4 CTRPv2 AAC 0.21 1e-08
mRNA SH3TC1 CTRPv2 AAC 0.21 1e-08
mRNA DYRK1B CTRPv2 AAC 0.21 1e-08
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