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tandutinib

Synonyms

SourcesNames Used
CTRPv2tandutinib
PharmacoGx tandutinib

External IDs

DatabaseIdentifier
Smiles: COc1cc2c(ncnc2cc1OCCCN3CCCCC3)N4CCN(CC4)C(=O)Nc5ccc(OC(C)C)cc5
Pubchem: 3038522

Annotated Targets

KIT, CSF1R, FLT3, PDGFD, PDGFRB

Cell lines tested with tandutinib

831 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to tandutinib


Feature TypeStandardized
Nominal ANOVA
mRNA GOLGA8M CTRPv2 AAC 0.33 7e-22
mRNA TIFAB CTRPv2 AAC 0.31 2e-19
mRNA PRSS57 CTRPv2 AAC 0.32 3e-19
mRNA DCANP1 CTRPv2 AAC 0.3 2e-18
mRNA GOLGA8J CTRPv2 AAC 0.29 4e-16
mRNA ITGAL CTRPv2 AAC 0.29 8e-14
mRNA PDGFRA CTRPv2 AAC 0.26 3e-13
mRNA RP11-231C18.3 CTRPv2 AAC 0.25 1e-12
mRNA CFD CTRPv2 AAC 0.25 5e-12
mRNA FLT3 CTRPv2 AAC 0.23 3e-11
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